Clinical Research Coordinator University of Chicago Chicago, Illinois, United States
Type 1 diabetes (T1D) affects around 5-10% of people with diabetes and can develop at any age. T1D is caused by insulin deficiency resulting from autoimmune destruction of the pancreatic beta cells. T1D genetics research has revealed a spectrum of disease variants that span between high impact, rare alleles that cause monogenic disease, and common alleles of low effect. T1D individuals with possible monogenic forms of the disease will often have other autoimmune conditions in addition to T1D or have family members with T1D. This poster will highlight for diabetes care and education specialists the unique aspects of the clinical presentation, determine which patients may benefit from research based genetic testing, and help accelerate precision medicine approaches to T1D.
